Why crystal meth abuse gives one a gaunt look

Why crystal meth abuse gives one a gaunt look

Scientists have probably figured out why methamphetamine (also known as meth or crystal meth) abuse gives people a gaunt look or induces striking changes in their physical features. According to a study by the scientists from the Italian Institute of Technology and UC Irvine, published in the open-access online journal PLOS ONE, meth abuse leads to stark abnormalities in the fat metabolism of cells.

This malfunction triggers a rise in a type of molecule in the cells that causes premature aging and cell death. Further research has revealed that crystal meth by damaging the brain and other body organs causes diseases related to aging, such as coronary atherosclerosis (hardening of the arteries) and pulmonary fibrosis (scarring of the lungs). Therefore, it is essential to understand the consequences of abusing crystal meth to avert the above-mentioned adverse effect.

As crystal meth is a very addictive drug, it has the potential to cause a long-term and profound impact on the brain. Besides boosting energy and reducing appetite, scientists have now proven that crystal meth is responsible for abnormal and rapid aging of the cells. Due to the above reasons, it is quite common for people abusing crystal meth to have a gaunt look.

Understanding cell aging process

The cell aging process is initiated by a particular protein known as nuclear factor kappa beta. As this protein regulates deoxyribonucleic acid (DNA) of other proteins, it is very important for the functioning of the human body. However, meth-induced signaling overwhelms the nuclear factor kappa beta that triggers the excessive production of cell-aging and pro-inflammatory molecules known as ceramide, which regulates energy production and the use of nutrients in a cell. As the quantity of the lipid is suddenly amplified, all other aspects of metabolism also speed up automatically.“We found this signaling process to be key for advanced cellular aging,” as per Professor Daniele Piomelli, Louise Turner Arnold Chair, Neurosciences, UCI.

By accelerating cellular senescence, it has become obvious that the abnormalities due to cell aging and death can become a very threatening factor for people. Researchers believe that the findings can open a new chapter in the studies related to aging and premature death of the cells.

“These results suggest new therapeutic strategies to reduce the adverse consequences of meth abuse and improve the effectiveness of abstinence treatments,” according to Piomelli. Considering the fact that over 12.3 million Americans in the age group 12 and above have tried meth at least once by 2016, according to the National Institute on Drug Abuse (NIDA), the findings of the above study are crucial for developing effective treatments.

The current research on inhibiting premature cell aging could lead to more general and fundamental research such as discovery of new molecules that can slow down the natural aging process as well. That can really have an impact on people because a lot of stress is already being provided to find a cure for aging.

Medical detox helps in getting back to normalcy

Even when there are some inhibitors that can slow down the process of abnormal cell damage due to meth abuse, the other effects of abuse remain intact. Anxiety, confusion, insomnia, mood disturbances and violent behavior are some of the effects that can occur due to continued meth abuse.

The best way to get rid of these adverse effects of meth abuse is to have a detox and start a life without the ill effects of meth. Medically assisted detox could be the right choice for the people abusing meth because through a combination of psychological and meth-addiction behavioral therapies, such as cognitive-behavioral and contingency-management treatment and therapeutic interventions, the detox and rehab centers in California can offer a safe detox and lasting recovery from crystal meth abuse.

Get treated for meth abuse

A quick step to seek medical assistance can go a long way in helping people suffering from addiction to crystal meth to get back to normal before meth wreaks havoc in their lives. Meth abuse can destroy anyone and professional treatment is the best way to stop the destruction.

If you know someone who may need treatment to get rid of meth abuse, seek help from the professional addiction treatment centers in California. You can get in touch with California Detox Helpline to get instant help. Call us at our 24/7 helpline number 855-780-2495 or chat online to get the assistance.